ARBRE-MOBIEU is co-organizing the FEBS Practical Course Hydrodynamic and thermodynamic analysis of biological macromolecules and their interactions, that will be held in Prague at the Faculty of Science, Charles University, and also at the BIOCEV research centre.
The course is taking place from September 23 until September 28. Applications are open until June 30, 2018 at https://biomacromoldynamics2018.febsevents.org.
Applications for the FEBS Youth Travel Fund fellowships are open until June 30, 2018.
The aim of the course is to provide theoretical, practical and data analysis training in several modern methods for monitoring and quantifying molecular interactions – analytical ultracentrifugation (AUC), isothermal titration calorimetry (ITC), surface plasmon resonance (SPR), microscale thermophoresis (MST), differential scanning fluorimetry (DSF) and fluorescence spectroscopy techniques; coupled with several other techniques used for detecting molecular interactions and characterization of biomolecules, i.e. dynamic light and small-angle X-ray scattering (DLS, SAXS), and structural mass spectrometry (cross-linking, H/D-exchange MS).
The course will provide brief theoretical introduction to the biophysical concepts underlying these methods, practicalities to prepare samples and set-up experiments, experimental demonstrations performed on state-of-art instruments present in the Centre of Molecular Structure, BIOCEV and at the Faculty of Science, Charles University.
Most importantly, the course will also provide theoretical introduction to basic and advanced data analysis methods that will be utilized within the practical half of the workshop including hands-on data analysis, using both tutorials with sample data and real data analysis (including one-on-one sessions with course tutors). The course will put emphasis on the complementarity of these different methods in the field of macromolecular biology and on the combined analysis of datasets coming from different methods. Practical data analysis will be demonstrated using the computational tools SEDFIT, SEDPHAT, GUSSI, EVILFIT and NITPIC.
5 out of the 13 speakers/organizers of this course are active ARBRE-MOBIEU members and will receive the support from COST. These grants are provided under the rules laid out by the COST Vademecum in what concerns the support of training schools.
Fot the course participants, several FEBS Youth Travel Fund (YTF) fellowships are available. A FEBS YTF grant may be up to a maximum of 800 € per person and is to be used to fully cover the registration fee including accommodation and meals (250 €), and support the travel costs. Please, check your eligibility here, and remember that if you are not yet a member of a national biochemistry FEBS constituent society, you may consider to become one to be eligible to apply.
Details about how to apply for YTF can be found here and supporting documents should be uploaded upon registration for the course.
On behalf of the Course Organizers